Helm Health

cardiac · Hcy

Homocysteine

An amino acid in the blood that rises when B vitamins (B12, folate, B6) are low. Elevated levels are associated with cardiovascular risk and can be a clue to underlying B-vitamin status.

This page is general wellness education, not medical advice. Your own lab’s reference range and your clinician’s interpretation always take precedence.

Typical reference range

GroupGeneral range
AdultsNormal < ~15 umol/L

Optimal-band note: Some practitioners aim for homocysteine under ~10 umol/L; elevations often respond to B12, folate, and B6. Soft target, not a diagnostic threshold.

Units: umol/L. Ranges vary by lab and assay — read yours against the range printed on your own report.

What high Homocysteine can mean

  • B12/folate/B6 deficiency
  • Reduced kidney function
  • Hypothyroidism
  • Genetics (MTHFR)
  • Some medications

What low Homocysteine can mean

  • Generally not clinically concerning

Related markers

Sources